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The impact of such channels on neuron firing fee in nigral dopamine neurons is this sort of that administration of the KATP-channel antagonist glibenclamide at a 100 nM focus was ready to boost neuron firing charge by 34% (Garcia de Arriba et al 1999; Avshalumov et al 2005). KATP-channel activity also seems to become enhanced by extracellular adeno